"I used to run but 10 years ago stopped due to health issues. I started the product and in a few months was beginning to run small distances. Now, am training for a 5K and am absolutely thrilled."

Matt T.

Mitokatlyst^TM, the key ingredient in Mitokatlyst^TM – E, mimics a hormone that induces mitochondrial biogenesis, supports the synthesis of ATP for energy, protects mitochondria from damage and dysfunction, and supports optimal mitophagy. Use Mitokatlyst^TM to:

Support cardiovascular function including restoring and improving blood flow to the heart and muscle
Support strength and endurance of skeletal muscles
Promote efficient metabolic function by shifting to preferential lipid oxidation metabolism creating a fat-burning phenotype
Reduce perilipin-associated triglyceride accumulation in the liver
Help improve insulin sensitivity
Support renal filtration and transport functions
Supports a more healthy inflammatory response
Experience a Better Quality of Life, from the Inside Out

Mitokatlyst™ – E contains 50 mg of the ingredient, Mitokatlyst™, 98% pure (-)-epicatechin with less than 2% catechins.

Clinical studies have shown a precise dose of (-)-epicatechin at 98% purity may boost mitochondrial biogenesis resulting in increased energy, muscle regeneration, and improved metabolic function.

Made without wheat, gluten, corn, nuts, peanuts, sesame seeds, sulfites, mustard, soy or any animal byproduct.

Vegan. Non-GMO. Gluten Free. Halal. Kosher.

Inactive Ingredients include Microcrystalline Cellulose, Crospovidone, Citric Acid Monohydrate, Silicon Dioxide and Magnesium Stearate.

Manufactured in cGMP-certified facility with CMC standards and the following accreditations: USFDA, WHO-GMP, UNICEF, ISO 9001:2015, ISO 14001:2015, ISO 45000:2018, FSSC 22000, HACCP, SQF, SMETA, Halal, Kosher.

For details on the purity and quality of each batch of Mitokatylst -E, see Batch Info

Stir contents of one (1) sachet in 2 oz of water or sugar-free lemonade. You can also mix the sachet contents in a tablespoon of yogurt before consuming it. We suggest taking the product on an empty stomach, if possible. Take the contents of one (1) sachet in the morning and one (1) sachet at night.

Each box contains 60 sachets which constitute a 30-day supply.

Warning: Do not exceed the recommended dose. This product is not intended for pregnant or nursing mothers, children under age 18, and individuals with a known medical condition should consult a physician before using this or any other dietary supplement.

"Waking up less tired" "Discomfort in back reduced" "Doing more activity" "Less brain fog" "Fewer naps" "Steady energy" "Climbing stairs again" "Increased stamina" "Sleep is better" "Less mentally drained" "Best quality supplement" "More strength" "Faster recovery"

How mitochondrial biogenesis affects your health.

Mitochondrial biogenesis is the process by which cells create new mitochondria. It starts with the cell nucleus releasing hormones that trigger mitochondrial division and growth.

Does (-)- Epicatechin impact muscle regeneration? Results of our clinical study.

(−)- Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy.*

“Salugenesis is the automatic, evolutionarily conserved, ontogenetic sequence of molecular, cellular, organ system, and behavioral changes that is used by living systems to heal. It is a whole-body process that begins with mitochondria and the cell.”

Robert Naviaux

MD, PhD, University of California, San Diego & Co-Founder Mitochondrial Medicine Society (MMS)

Read the full article

I have the steady energy to get through my afternoons without needing an extra nap

Jim M.

Seeing a significant lessening of discomfort in my hands just after 9 weeks on the product.

Tina M.

After a few months,I noticed that I did not need a rest day after a long ride. Amazing! Thank you!

Cherry D

My brain fog seems to have reduced since being on the product.

Gordon N.

I think this is the best quality supplement for the mitochondria that I have come across.

Justin B.

Have a question about Mitokatlyst?

Mitokatlyst™- E is a natural, plant-based mitochondrial supplement and is manufactured in a US FDA-approved cGMP facility. The molecule Mitokatlyst™, the key ingredient in Mitokatylst™–E, is clinically proven to increase the quantity and quality of mitochondria (without cell proliferation), improve ATP production, protect mitochondria from damage and dysfunction, and support optimal mitophagy.

Mitokatlyst™-E defines a new, emerging category of mitochondrial catalysts; its unique mechanism of action is neither a mitochondrial cocktail nor an antioxidant.

Always consult your doctor before taking any nutraceutical or dietary supplements.

Your mitochondria are the powerhouses of your body. More than 90% of your body’s energy for various biological functions is generated inside these organelles. Every bite of food you eat is converted into adenosine triphosphate (ATP) in the inner membrane of your mitochondria. Energy is released when ATP is hydrolyzed into adenosine diphosphate (ADP). More energy is released when ADP is further converted to adenosine monophosphate (AMP).

This energy is used to improve blood flow and metabolic rate, improve regulation of blood sugar levels, and promote muscle protein synthesis. In addition, it may help reduce cholesterol levels, improve cardiovascular function, and support cognitive function.

After the age of 20, every decade, we begin to lose 10-15% of our mitochondria permanently, which is defined as aging. Combined with this loss, we also experience continuous insults, such as pollution, pesticides, stress, environmental toxins, and acute inflammation. This leads to decline in mitochondrial quality and quantity, which results in a downward spiral in bioenergetics, impacting all systems of our body, ranging from skeletal muscle, cardiovascular, metabolic, cognition, to aging of the skin and loss of hair.

Hence, protecting mitochondria from damage and improving the quantity and quality of mitochondria is vital for the body to function efficiently and optimally.

Yes, Mitokatlyst™–E is a mitochondrial supplement. This is a newly emerging category of mitochondrial catalysts; its mechanism of action is neither a mitochondrial cocktail nor an antioxidant.

The molecule Mitokatlyst™, the key ingredient in Mitokatylst™–E, is clinically proven to increase the quantity and quality of mitochondria (without cell proliferation), improve ATP production, protect mitochondria from damage and dysfunction, and support optimal mitophagy.

Note that mitochondrial cocktails may provide support to the mitochondria among other activities; however, they may not improve the quality or increase the quantity of mitochondria.

Always consult your doctor before taking any nutraceutical or dietary supplements.

Mitochondria are the primary organelles for energy production, generating over 90% of the energy required by biological processes in the human body. One can consider the mitochondria to be similar to furnaces that use the food we eat (the fuel) to produce energy.

In the modern era, antioxidants and dietary supplements have been identified that could provide fuel and support for mitochondria, helping keep the existing machinery running as efficiently as possible. The key benefits of increasing mitochondrial support could include enhanced physical energy, improved cardiovascular health, better cognitive function, and reduced chronic fatigue.

Mitochondrial fuels or cocktails mainly focus on the Electron Transport Chain (ETC) and/or the Tricarboxylic Acid Cycle (TCA) within mitochondria, which produce energy. Do note that these supplements may not create new healthy mitochondria, which are critical to producing sufficient energy required for healthy aging.

No, Mitokatlyst™–E is not a mitochondrial cocktail or an antioxidant – it is a mitochondrial catalyst.

Mitokatlyst™, a highly pure (98%) and stable molecule of (-)-Epicatechin – clinically demonstrates a novel mechanism of action that activates the body’s own machinery to build new, robust mitochondria (quality and quantity), without cell proliferation. In addition, it improves ATP production, protects mitochondria from damage and dysfunction, and supports optimal mitophagy.

The efficacy of Mitokatlyst™ is driven by a highly specific molecular structure, dose, and purity. Unlike structural analogs, which can be ineffective or even antagonistic, Mitokatlyst™provides targeted efficacy with an exceptional safety profile. Check out our Research page to see a list of peer-reviewed published papers.

Note that mitochondrial fuel supplements may provide support to the mitochondria among other activities; however, they may not create new mitochondria.

Always consult your doctor before taking any nutraceutical or dietary supplements.

The molecule Mitokatlyst™ in Mitokatlyst™-E is a mitochondrial catalyst, a newly emerging category of mitochondrial supplements. It is the first molecule – at a precise purity and usage – clinically proven to increase mitochondrial quantity, quality, and function, without cell proliferation. Additionally, it improves ATP production, protects mitochondria from damage and dysfunction, and supports optimal mitophagy

Note that while mitochondrial fuel supplements provide essential metabolic support, they primarily optimize existing organelles rather than stimulating the biogenesis of new mitochondria.

Always consult your doctor before taking any nutraceutical or dietary supplements.

Mitokatlyst™–E is different from other epicatechin supplements as it does not act as an antioxidant. The molecule Mitokatlyst™ in Mitokatlyst™-E – at a precise purity and usage – is clinically proven to increase mitochondrial quantity, quality, and function (without cell proliferation). Additionally, it improves ATP production, protects mitochondria from damage and dysfunction, and supports optimal mitophagy.

Other key differentiators include:

Mitokatlyst™–E is 98% pure (-)-Epicatechin with less than 2% Enantiomers and less than 0.1% Epigallocatechin-3-gallate (EGCG). Structural requirements for Mitokatylst™ activity are highly specific. Closely related structural analogs not only have no efficacy but can also antagonize the effect of this molecule. Other Epicatechin alternatives on the market contain unknown levels of catechins and EGCG (a known liver toxin at high doses).
(-)-Epicatechin is extremely unstable, and under normal conditions, it devolves into catechins. The Blue Oak Nutraceuticals proprietary manufacturing process stabilizes the molecule at 98% purity. Each batch is tested for purity and stability every 30 days, under high pressure, agitation, and temperature to ensure stability and purity.
The precise usage of Mitokatlyst™–E is based on human clinical studies. The basis of the typical 200 – 500 mg dose of other epicatechin alternatives on the market is unknown.
Mitokatlyst™–E is the result of 64 published papers, a combined 45+ years of research and multiple Phase 1 & 2 Clinical Studies by researchers led by BlueOakNx co-founder Sundeep Dugar, PhD.
Mitokatlyst™–E has an Exceptional Safety Profile based on clinical studies.
Mitokatlyst™–E is manufactured in a US FDA-approved cGMP facility with the following accreditations: USFDA, WHO-GMP, UNICEF, ISO 9001:2015, ISO 14001:2015, ISO 45000:2018, FSSC 22000, HACCP, SQF, Halal, Kosher, SMETA etc. Our internal product quality specifications meet or exceed ICH/USP guidelines.
Mitokatlyst™–E is free of heavy metals and is certified vegan, gluten-free, non-GMO and made without wheat, corn, nuts, peanuts, sesame seeds, sulfites, mustard, soy or any animal byproducts. Inactive ingredients include: Microcrystalline Cellulose, Crospovidone, Citric Acid Monohydrate, Silicon Dioxide, and Magnesium Stearate.

Always consult your doctor before taking any nutraceutical or dietary supplements.

Mitokatlyst™ – E contains 50 mg of the molecule, Mitokatlyst™, 98% pure (-)-Epicatechin with less than 2% catechins. At this purity (at a precise usage), the molecule does not act as an antioxidant or a mitochondrial fuel but as a mitochondrial catalyst.

Inactive Ingredients include Microcrystalline Cellulose, Crospovidone, Citric Acid Monohydrate, Silicon Dioxide and Magnesium Stearate.
Made without wheat, gluten, corn, nuts, peanuts, sesame seeds, sulfites, mustard, soy, or any animal byproduct. Vegan. Non-GMO. Gluten Free.
Manufactured in a cGMP facility with the following accreditations: USFDA, WHO-GMP, UNICEF, ISO 9001:2015, ISO 14001:2015, ISO 45000:2018, FSSC 22000, HACCP, SQF, Halal, Kosher, Gluten free, SMETA, etc.
For details on the purity and quality of each batch of Mitokatylst -E, see Bach Info.

Always consult your doctor before taking any nutraceutical or dietary supplements.

The polyphenols and flavonoids in green tea and chocolate are antioxidants that neutralize free radicals, reduce inflammation, and protect cells from damage. Their mechanism of action does not signal the cell nucleus to create more mitochondria

The mechanism of action of Mitokatlyst™–E at its precise purity (98% plus) and usage (50 mg twice daily) is of a mitochondrial catalyst. Its unique mechanism of action has been clinically proven to signal the cell nucleus to increase the quantity and quality of mitochondria (without cell proliferation), improves ATP production, protects mitochondria from damage and dysfunction, and supports optimal mitophagy.

Always consult your doctor before taking any nutraceutical or dietary supplements.

The excipients add to the stability and absorption properties of the product. We do a bioburden test to confirm the absence of infectious agents and ensure safety and purity.

The use has been tested and calibrated for ranges that cover most populations.

For a body weight of 30-35 kg (approximately 66 – 77 lbs), the recommended use is 50 mg per day. This translates to one sachet in the morning or ½ sachet in the morning and ½ sachet in the evening. Once a sachet is opened, it should be clipped tightly and placed in the freezer to maintain product stability until needed.

Above 35 kgs (approximately 77 lbs), the recommended use is 100 mg per day. This translates to one sachet in the morning and one sachet in the evening.

As always, consult your medical practitioner before taking this or any other supplement.

Clinical studies using Mitokatlyst™ have demonstrated improvements in muscle strength and endurance in as little as 90-120 days.

Individual results may vary and differ from a typical user’s experience and is not intended to represent or guarantee that every user will achieve the same or similar results.

Always consult your doctor before taking any nutraceutical or dietary supplements, including this one.

Starting at the age of 20, every decade we lose 10-15% of our mitochondria permanently – this is defined as aging. Experiencing the permanent loss of mitochondria, along with continuous insults, such as biological, physical, pollution, pesticides, stress, environmental toxins, and inflammation, leads to an additional decline in mitochondrial quality and quantity, resulting in a downward spiral in bioenergetics.

Mitokatlyst™-E offers a solution to this downward bioenergetics spiral. The key ingredient in Mitokatlyst™-E is the molecule Mitokatlyst™, which contains the same precise purity and dosage of (-)-Epicatechin that has been utilized in clinical studies and research published by BlueOakNx scientists. This molecule is clinically known to stimulate an increase in the quantity and quality of mitochondria (without cell proliferation), improve ATP production, protect mitochondria from damage and dysfunction, and promote optimal mitophagy.

Always consult your doctor before taking any nutraceutical or dietary supplements.

Yes, you can stir the sachet contents in 2 ounces of water or unsweetened lemonade. You can also mix the sachet contents in a tablespoon of yogurt before consuming it. Do not mix it into hot drinks. Consume immediately after mixing.

Take the contents of one sachet in the morning and one at night, or as recommended by your doctor. Suggest taking it on an empty stomach, if possible.

Always consult your doctor before taking any nutraceutical or dietary supplement, including this one.

No. There are no expected side effects from Mitokatlyst™ – E.

BlueOakNx products are not intended for pregnant or nursing mothers. Children under 18 and individuals with a known medical condition should not take BlueOakNx products without first consulting a physician.

We recommend waiting 60 mins after taking Mitokatlyst™-E to consume green tea.

BlueOakNx co-founder Sundeep Dugar, PhD, has led preclinical and clinical research for over 16 years and has proven this unique mechanism of action of the Mitokatlyst™ molecule.

Check out our Research page to see a list of peer-reviewed published papers.

Since launch, independent clinical trials and PROs are underway by clinicians and researchers in various universities and teaching hospitals in the U.S., Sweden, and Scotland, among other countries.

BlueOakNx co-founder Sundeep Dugar, PhD, has led preclinical and clinical research for over 16 years and has proven this unique mechanism of action of the Mitokatlyst™ molecule.

Check out our Research page to see a list of peer-reviewed published papers.

Independent clinical trials and PROs are being conducted by clinicians and researchers in various universities and teaching hospitals in the U.S., Sweden, and Scotland, among other countries.

Check out our Research page to see a list of peer-reviewed published papers.

Typically, dietary supplements are not covered by insurance.

A Public Benefit Corporation is created to protect the long-term mission and vision of a company, where all stakeholders (customers, employees and investors) are given equal consideration. Unlike traditional corporations, which are legally required to maximize financial returns to shareholders, a Public Benefit Corporation can stay true to its mission and vision while also ensuring sustainability of the business.

We recommend our quarterly subscription (3 boxes paid for and shipped in one shipment) as it is our most cost-effective option with the highest discounts.

When you sign up for a monthly or quarterly subscription, you can cancel anytime before your next shipment. Please contact our Customer Success Team at care@blueaoknx.com for assistance with any more questions you may have.

You can only use one coupon at a time. Monthly and quarterly subscriptions are already discounted. Note that if you do not have a coupon code from your practitioner, we encourage you to ask your practitioner to contact us. You can also find coupons in our newsletter. Sign up below.

As stated in the Terms of Service, this product is non-returnable as it is an ingestible product; if the product arrives damaged or defective, you can request a refund or replacement.

Please take clear photos of the damaged item(s) and email them to care@blueoaknx.com with your order number. You will be sent a shipping label to return the damaged item(s). Once we receive the damaged item(s), your return will be processed and you will either receive a credit on your credit card within 7-14 days or a new shipment will be sent to you, as per your request.

Currently, our products are available for purchase directly through our website and in the United States only. Subscribe to our newsletter to stay up to date on availability of our products in your country.

Yes, shipping is free in the U.S.; we will find the fastest shipping based on your mailing address. We do not ship outside the U.S.

Currently, our products are sold in the United States. Subscribe to our newsletter to stay up to date on availability of our products in your country.

How Mitokatlyst - E works

Ingredients

Recommended use