The symposium will highlight advances across three interconnected themes.

• Mitochondrial Genetics and Cellular Signaling in Brain Health will examine how mitochondrial DNA variation and bioenergetic function shape neural performance and disease risk.
• Mitochondrial Psychobiology: Stress, Development, and Neuroplasticity will explore how stress and early life experience influence mitochondrial dynamics and long-term mental health.
• Metabolic Psychiatry and Mitochondrial Therapeutics: From Diet to Drug Development will focus on emerging nutritional, metabolic, and pharmacologic strategies to target mitochondrial pathways implicated in psychiatric conditions.